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1

Schwefel und Selen: Bedeutung der Oxidationsstufe für Struktur und Funktion von Proteinen

Claus Jacob, Gregory I. Giles, Niroshini M. Giles, Helmut Sies

Journal:

Angewandte Chemie

Year:

2003

Language:

german

File:

PDF, 402 KB

german, 2003

2

Sulfur and Selenium: The Role of Oxidation State in Protein Structure and Function

Claus Jacob, Gregory I. Giles, Niroshini M. Giles, Helmut Sies

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 396 KB

english, 2003

3

Sulfur and Selenium: The Role of Oxidation State in Protein Structure and Function

Claus Jacob, Gregory I. Giles, Niroshini M. Giles, Helmut Sies

Journal:

Year:

2004

File:

PDF, 52 KB

2004

4

Metal and Redox Modulation of Cysteine Protein Function

Niroshini M Giles, Aaron B Watts, Gregory I Giles, Fiona H Fry, Jennifer A Littlechild, Claus Jacob

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

5

Reactive sulphur species: an in vitro investigation of the oxidation properties of disulphide S-oxides

GILES, Gregory I., TASKER, Karen M., COLLINS, Catriona, GILES, Niroshini M., O’ROURKE, Elizabeth, JACOB, Claus

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

6

A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress

Aimee Landar, Joo-Yeun Oh, Niroshini M. Giles, Amanda Isom, Marion Kirk, Stephen Barnes, Victor M. Darley-Usmar

Journal:

Free Radical Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 471 KB

english, 2006

7

Electrochemical Evaluation of Molecular Mimics of Glutathione Peroxidase

Gregory Ian Giles, Sweta Arya, Siddharth Patel, Niroshini Manthri Giles

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 156 KB

english, 2010

8

Targeting oxidative stress-related diseases: organochalcogen catalysts as redox sensitizers

Niroshini M Giles, Gregory I Giles, Janet E Holley, Nick J Gutowski, Claus Jacob

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

9

The Molecular Design of S-Nitrosothiols as Photodynamic Agents for Controlled Nitric Oxide Release

Niroshini M. Giles, Sweta Kumari, Bevan P. Gang, Chun W. W. Yuen, Emilie M. F. Billaud, Gregory I. Giles

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 352 KB

english, 2012

10

A hydrogen peroxide electrode assay to measure thiol peroxidase activity for organoselenium and organotellurium drugs

Niroshini M. Giles, Sweta Kumari, Rosemary A. Stamm, Siddharth Patel, Gregory I. Giles

Journal:

Analytical Biochemistry

Year:

2012

Language:

english

File:

PDF, 453 KB

english, 2012

11

Multiple roles of cysteine in biocatalysis

Niroshini M Giles, Gregory I Giles, Claus Jacob

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

12

Redox catalysts as sensitisers towards oxidative stress

Niroshini M Giles, Nick J Gutowski, Gregory I Giles, Claus Jacob

Journal:

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

13

Intracellular Targeting and Pharmacological Activity of the Superoxide Dismutase Mimics MnTE-2-PyP 5+ and MnTnHex-2-PyP 5+ Regulated by Their Porphyrin Ring Substituents

Aitken, Jade B., Shearer, Emily L., Giles, Niroshini M., Lai, Barry, Vogt, Stefan, Reboucas, Julio S., Batinic-Haberle, Ines, Lay, Peter A., Giles, Gregory I.

Journal:

Inorganic Chemistry

Year:

2013

Language:

english

File:

PDF, 835 KB

english, 2013

14

Effect of Tryptophan Insertions on the Properties of the Human Group IIA Phospholipase A 2 : Mutagenesis Produces an Enzyme with Characteristics Similar to Those of the Human Group V Phospholipase A 2†

Beers, Stephen A., Buckland, Andrew G., Giles, Niroshini, Gelb, Michael H., Wilton, David C.

Journal:

Year:

2003

Language:

english

File:

PDF, 438 KB

english, 2003

15

Multifunctional redox catalysts as selective enhancers of oxidative stress

FryThese authors contributed equall, Fiona H., Holme, Andrea L., Giles, Niroshini M., Giles, Gregory I., Collins, Catriona, Holt, Kim, Pariagh, Sandra, Gelbrich, Thomas, Hursthouse, Michael B., Gutows

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

16

Electrochemical, in vitro and cell culture analysis of integrated redox catalysts: implications for cancer therapy

Giles, Gregory I., Giles, Niroshini M., Collins, Catriona A., Holt, Kim, Fry, Fiona H., Lowden, Philip A. S., Gutowski, Nicholas J., Jacob, Claus

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

17

Accumulation of 15-deoxy-Δ 12,14 -prostaglandin J 2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction

Oh, Joo Yeun, Giles, Niroshini, Landar, Aimee, Darley-Usmar, Victor

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 619 KB

english, 2008

18

Modification of lipids by reactive oxygen and nitrogen species: the oxy–nitroxy–lipidome and its role in redox cell signaling

Landar, Aimee, Giles, Niroshini, Zmijewski, Jaroslaw W, Watanabe, Nobuo, Oh, Joo–Yeun, Darley–Usmar, Victor M

Journal:

Future Lipidology

Year:

2006

Language:

english

File:

PDF, 581 KB

english, 2006

19

Quadruply Stranded Metallo-Supramolecular Helicate [Pd 2 (hextrz) 4 ] 4+ Acts as a Molecular Mimic of Cytolytic Peptides

McNeill, Samantha M., Giles, Niroshini M., Preston, Dan, Jones, Peter P., Crowley, James D., Giles, Gregory I.

Journal:

Chemical Research in Toxicology

Year:

2020

File:

PDF, 2.56 MB

2020

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